Background:

The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides.

Applications:

ELISA, WB, IHC

Name of antibody:

THOP1

Immunogen:

Fusion protein of human THOP1

Full name:

thimet oligopeptidase 1

Synonyms:

TOP; MP78; EP24.15; MEPD_HUMAN

SwissProt:

P52888

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

79 kDa

WB Positive control:

Human cerebrum tissue and Human fetal brain tissue lysates

WB Recommended dilution:

500-2000