WB Recommended dilution:

100-500

IHC Recommend dilution:

10-50

SwissProt:

P33778

Synonyms:

H2B.1; H2B/f; H2BFF; HIST1H2BB

Full name:

H2B clustered histone 3

Immunogen:

KLH conjugated synthetic peptide derived from human H2BC3

Name of antibody:

H2BC3

Applications:

ELISA, WB, IHC

Back   ground:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]