Background:

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling.

Applications:

ELISA, WB, IHC

Name of antibody:

MUC1

Immunogen:

Synthetic peptide of human MUC1

Full name:

mucin 1, cell surface associated

Synonyms：

EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC

SwissProt:

P15941

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

122 kDa

WB Positive control:

HT-29 cells

WB Recommended dilution:

200-1000