Background:

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Applications:

WB, IHC, IF

Name of antibody:

PMEPA1

Immunogen:

Synthesized peptide derived from internal of human TMEPA.

Full name:

prostate transmembrane protein, androgen induced 1

Synonyms：

STAG1; TMEPAI

SwissProt:

Q969W9

IHC positive control:

Human prostate tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

32 kDa

WB Positive control:

HT-29 cells lysate

WB Recommended dilution:

500-3000

IF positive control:

Huvec cells

IF Recommend dilution:

100-500