Background:

The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications:

ELISA, IHC

Name of antibody:

VSX1

Immunogen:

Fusion protein of human VSX1

Full name:

visual system homeobox 1

Synonyms:

PPD; KTCN; PPCD; RINX; KTCN1; PPCD1; CAASDS

SwissProt:

Q9NZR4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and human gastric cancer

IHC Recommend dilution:

25-100